QIAGEN Reports Strong Third Quarter 2009 Results

16% Revenue Growth on Constant Exchange Rates
15% Organic Revenue Growth
31% Operating Margin, adjusted
$0.26 Adjusted EPS


QIAGEN N.V. (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) today announced the results of operations for the third quarter and the nine-month period ended September 30, 2009.

The reported net sales and the adjusted earnings per share for the third quarter 2009 exceeded the guidance provided by the Company on August 11, 2009.

Third Quarter 2009 Results

QIAGEN's Third Quarter 2009 (in US$ millions, except per share information)
Q3 2009 Q3 2008 Growth

Net sales 259.7 230.8 13 %
Net sales at constant exchange rates 268.7 230.8 16 %
Operating income, adjusted 81.8 66.8 22 %
Net income, adjusted 53.5 42.4 26 %
EPS, adjusted (US$) 0.26 0.21 24 %



The Company reported that consolidated net sales for its third quarter 2009 increased 13% to $259.7 million from $230.8 million in the same quarter of 2008. Excluding the unfavorable impact from foreign currency exchange rates, net sales for the third quarter 2009 would have increased 16%. The reported operating income for the quarter increased 40% to $53.4 million from $38.2 million in the same quarter of 2008, and net income for the quarter increased 81% to $37.7 million from $20.8 million in the same quarter of 2008. Diluted earnings per share for the third quarter increased 80% to $0.18 in 2009 from $0.10 in 2008.

On an adjusted basis, third quarter operating income increased 22% to $81.8 million in 2009 from $66.8 million in 2008, and third quarter 2009 adjusted net income increased 26% to $53.5 million from $42.4 million in 2008. Adjusted diluted earnings per share increased 24% to $0.26 in the third quarter 2009 from $0.21 in 2008.

Nine-Month Period 2009 Results

For the nine-month period ended September 30, 2009, net sales increased 10% to $720.7 million compared to $655.8 million in the same period of 2008. Operating income as reported for the nine months ended September 30, 2009 increased 30% to $137.3 million from $105.2 million for the same period in 2008. Net income increased 45% to $93.3 million from $64.4 million in 2008, and diluted earnings per share increased 45% to $0.45 in 2009 from $0.31 in 2008.

On an adjusted basis, operating income for the nine-month period ended September 30, 2009 increased 14% to $212.7 million in 2009 from $186.1 million in 2008, and adjusted net income increased 19% to $142.0 million from $119.6 million. Adjusted diluted earnings per share in the nine months ended September 30, 2009 increased 19% to $0.69 per share from $0.58 per share in the same period of 2008.

QIAGEN's third quarter and nine-month period 2009 results include the results of operations from the Company's recent acquisitions, the most significant of which was DxS Ltd., acquired in September 2009, and Corbett Life Science, acquired in July 2008. Reconciliations of reported results determined in accordance with generally accepted accounting principles (GAAP) to adjusted results are included in the tables accompanying this release.

"We are very pleased with our financial performance in the third quarter of 2009," said Peer Schatz, QIAGEN's Chief Executive Officer. "We saw strong growth in revenues, operating margins and adjusted net income - all of which exceeded our guidance. In addition, our organic revenue growth came in very strong at 15%."

"Revenue growth was highest in sales to customers in molecular diagnostics (approximately 50% of total revenues) followed by sales to customers in pharma (approximately 21% of total revenues), in applied testing (approximately 6% of total revenues) and in academia (approximately 23% of total revenues). Growth of our sales to customers in molecular diagnostics was fueled by strong sales of our "prevention" products (primarily HPV screening),"personalized health care" assays (including our KRAS testing solutions) and profiling solutions (including our influenza and other infectious disease assays). Sales to customers in the pharmaceutical and biotech industry conducting clinical development continued to experience solid growth and sales to customers in pharma discovery are improving. The academic research markets continued to perform solidly and we are looking forward to the effect of the stimulus programs which are expected for 2010."

"The markets we serve demonstrated robust demand and solid economic trends. We are very pleased with the strategic momentum we were able to build since the announcement of our second quarter results in August. Since August we have announced the following acquisitions:
The pending acquisition of SABiosciences will add to QIAGEN a portfolio of PCR-based, pathway-focused panels that represent highly efficient solutions for pathway- and disease-biomarker discovery and development in pharmaceutical and biomedical research. The efforts associated with the validation of such biomarkers can at the same time serve as engines for novel content for molecular diagnostics.

The acquisition of DxS Ltd. combines two leadership positions to create a very powerful leader in a transformational area of healthcare: personalized healthcare.

Both transactions are key elements of our strategy to lead in molecular diagnostics-based prevention, profiling and personalized healthcare. These three pillars of our molecular diagnostics strategy are expected to significantly shape and contribute to future improvements in healthcare and have the potential to provide significant benefits to patients as well as exceptional value for payers, providers, and the pharmaceutical industry."

"QIAGEN experienced a successful third quarter. Reported revenues and adjusted earnings per share exceeded our expectations," said Roland Sackers, QIAGEN's Chief Financial Officer. "Assuming constant exchange rates for both quarters, and adjusted for the divesture of certain assets related to our activities in HLA diagnostics (transplantation diagnostics), revenue growth was 18% and was fueled by a strong organic growth of 15% and a positive contribution of 3% from acquisitions.

Our consumable products portfolio contributed 12% growth (16% at constant exchange rates) and our sales of instrumentation products recorded a growth rate of 18% (23% at constant exchange rates). Net sales in the Americas for the third quarter 2009 represented approximately 51% of our overall business and recorded a growth rate of 12% (15% at constant exchange rates) and European sales, which represent approximately 35% of our revenues, showed a growth rate of 16% (24% at constant exchange rates). Net sales in Asia remained strong, showing a growth rate of 41% (37% at constant exchange rates)."

Increase of Fiscal Year 2009 Guidance Range

Based on the successful first nine months and a positive outlook for the rest of the year, QIAGEN is increasing its expectations for adjusted diluted earnings per share for the fiscal year 2009 from the previous range of $0.86 to $0.90 (based on a weighted average number of fully diluted shares outstanding of approximately 214 million following the equity offering in September 2009) to now between $0.88 and $0.90 based on foreign currency exchange rates as of January 31, 2009.

QIAGEN - Sample and Assay Technologies Highlights

In September, QIAGEN acquired DxS Ltd., a developer and manufacturer of companion diagnostic products (CDx) for Personalized Healthcare (PHC). With this acquisition, QIAGEN has added to its own activities in CDx and taken a strong leadership position in the new era of PHC. The Company believes it offers all the required elements to help drive and shape this rapidly emerging trend in healthcare. The acquisition of DxS brings to QIAGEN a portfolio of molecular diagnostic assays and intellectual property, as well as a deep pipeline of active or planned companion diagnostic partnerships in oncology with many of the leading pharmaceutical companies, including Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, AstraZeneca and others. These assets complement QIAGEN's strong existing portfolio of personalized healthcare diagnostic solutions and are very synergistic with QIAGEN's sample and assay technologies.
In November, QIAGEN announced that it is in the process of acquiring SABiosciences. This transaction will add to QIAGEN's product offering a leading portfolio of PCR-based, disease and pathway-based panels that play key roles in biomedical research and the development of future drugs and diagnostics. The offerings from SABiosciences can significantly increase QIAGEN's footprint in the rapidly emerging segment of molecular analysis-based clinical development in pharmaceutical and biomedical research. In addition, the use of these panels and the resulting validation of select biomarkers from these panels by institutions conducting biomedical and pharmaceutical research has the potential to serve as a unique engine to support the expansion of the test menu for QIAGEN's diagnostics platforms - in particular in the area of personalized health care but also in prevention and profiling. As such, this transaction is highly synergistic with QIAGEN's activities in the fast growing segments of solutions for pharmaceutical development and molecular diagnostics.

In September, QIAGEN and Merck & Co., Inc. announced the creation of a joint program to increase access to HPV vaccination and HPV DNA testing in some of the poorest areas of the world. This initiative is the first collaboration of a vaccine manufacturer and a molecular diagnostics company to address the burden of cervical cancer with a comprehensive approach. Representing a combined value of approximately $600 million based on current U.S. prices, the commitments of QIAGEN and Merck were highlighted among a select group of corporate initiatives announced at the annual meeting of the Clinton Global Initiative in September. QIAGEN intends to add to its existing one million test donation program by providing the digene HC2 HPV DNA Test (as known as the digene HPV Test) and a new HPV DNA test that is currently in development for use specifically in the developing world to screen an additional 500,000 women. In addition, Merck intends to provide up to five million free doses of its cervical cancer vaccine, GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16 and18) Vaccine Recombinant].

In September, QIAGEN opened its new Asia headquarters in Zhangjiang High-Tech Park, Pudong, Shanghai, China. QIAGEN established Shanghai as the location for its Asia headquarters in 2006. Resources and employees that were previously spread across different locations have been brought together at the new site in Zhangjiang High-Tech Park - which has emerged as the biotechnology hub of China. Zhangjiang High-Tech Park is home to 15 multinational pharmaceutical R&D centers, 32 Contract Research Organization (CRO) companies, 29 major pharma manufacturing plants and over 200 biotech-pharma companies. QIAGEN's new facility provides better access to the Company's new technologies and applications and reduces delivery time to thousands of scientists working in the Park.

In the first nine months of 2009, QIAGEN launched more than 48 new products in the area of Sample & Assay Technologies including a range of applications used to analyze genetic differences between individuals or cells, the Type-it® HRM PCR Kit and Rotor-Gene® ScreenClust HRM Software. HRM (high resolution melting) technology enabling fast, accurate genotyping results. In addition QIAGEN launched a new PCR-based Influenza A/H1N1 test that enables both the highly sensitive and specific detection of the novel Influenza A/H1N1, the virus that causes "swine flu", as well as of all other known Influenza A and B virus strains and several QIAsafe DNA Blood Products, the first dry blood storage solutions available on a matrix, based on Biomatrica's innovative SampleMatrix® technology.
In September, QIAGEN placed 31.6 million shares (including the full exercise of an over-allotment option) at a price of $20.25 per share. QIAGEN used and expects to use the net proceeds of approximately $624 million to fund the acquisition of DxS Ltd. as well as potential future acquisitions, to strengthen its balance sheet and for general corporate purposes.
In October, QIAGEN started the relocation of its activities in Brisbane and Sydney to other locations of the Company, primarily to QIAGEN Instruments AG in Switzerland. The restructurings follow the acquisition of Corbett in 2008 and consolidate QIAGEN's instrument manufacturing activities. The closure and relocation is intended to be completed in the second quarter of 2010 and is expected to result in an increase in QIAGEN's future profitability. QIAGEN expects to incur total restructuring charges of approximately $4 to $5 million before taxes for the remainder of fiscal 2009 and fiscal 2010.
Conference Call and Webcast Details

Detailed information on QIAGEN's business and financial performance will be presented during its conference call on November 10, 2009 at 9:30am ET. The corresponding presentation slides will be available for download on the Company's website at www.qiagen.com/goto/ConferenceCall. A webcast of the conference call will also be available at www.qiagen.com/goto/ConferenceCall.

Use of Adjusted Results

QIAGEN has regularly reported adjusted results to give additional insight into its financial performance as well as considered results on a constant currencies basis. Adjusted results should be considered in addition to the reported results prepared in accordance with generally accepted accounting principles, but should not be considered as a substitute. The Company believes certain items should be excluded from adjusted results when they are outside of its ongoing core operations, vary significantly from period to period, or affect the comparability of results with the Company's competitors and its own prior periods. Reconciliations of reported results to adjusted results are included in the tables accompanying this release.


About QIAGEN

QIAGEN N.V., a Netherlands holding company, is the leading global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA and proteins from biological samples such as blood or tissue. Assay technologies are used to make these isolated biomolecules visible. QIAGEN has developed and markets more than 500 sample and assay products as well as automated solutions for such consumables. The Company provides its products to molecular diagnostics laboratories, academic researchers, pharmaceutical and biotechnology companies, and applied testing customers for purposes such as forensics, animal or food testing and pharmaceutical process control. QIAGEN's assay technologies include one of the broadest panels of molecular diagnostic tests available worldwide. This panel includes the first FDA-approved test for human papillomavirus (HPV), the primary cause of cervical cancer. QIAGEN employs more than 3,300 people in over 30 locations worldwide. Further information about QIAGEN can be found at http://www.qiagen.com/.

Certain of the statements contained in this news release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, markets, strategy or operating results are forward-looking, such statements are based on current expectations that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations and risks of dependency on logistics), variability of operating results, the commercial development of the applied testing markets, clinical research markets and proteomics markets, women's health/HPV testing markets, nucleic acid-based molecular diagnostics market, and genetic vaccination and gene therapy markets, changing relationships with customers, suppliers and strategic partners, competition, rapid or unexpected changes in technologies, fluctuations in demand for QIAGEN's products (including fluctuations due to general economic conditions, the level and timing of customers' funding, budgets, and other factors), our ability to obtain regulatory approval of our infectious disease panels, difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products, the ability of QIAGEN to identify and develop new products and to differentiate its products from competitors' products, market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses. In addition certain statements contained in this news release are based on company assumptions, including, but not limited, to revenue allocations based on business segments. For further information, refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission (SEC).
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QIAGEN N.V.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME
(unaudited)
Three months
ended September 30,
(in thousands, except per share data)

2009 2008
Net sales $ 259,659 $ 230,800
Cost of sales 86,647 77,861
Gross profit 173,012 152,939

Operating expenses:
Research and development 26,747 24,073
Sales and marketing 60,719 55,972
General and administrative, integration and other 27,805 29,868
Purchased in-process research and development - 830
Acquisition related intangible amortization 4,387 4,018
Total operating expenses 119,658 114,761

Income from operations 53,354 38,178

Other income (expense):
Interest income 678 2,095
Interest expense (7,405) (9,194)
Other income, net 2,692 (3,233)
Total other expense (4,035) (10,332)

Income before provision for income taxes and noncontrolling interest 49,319 27,846
Provision for income taxes 11,629 6,679
Net income 37,690 21,167
Less: Noncontrolling interest - 376
Net income attributable to QIAGEN N.V. $ 37,690 $ 20,791

Weighted average number of diluted common shares 208,316 204,600

Diluted net income attributable to QIAGEN N.V. per common share $ 0.18 $ 0.10

Diluted net income attributable to QIAGEN N.V. per common
share, adjusted $ 0.26 $ 0.21




QIAGEN N.V.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME
(unaudited)

Nine months
ended September 30,
(in thousands, except per share data)

2009 2008
Net sales $ 720,748 $ 655,794
Cost of sales 241,787 213,555
Gross profit 478,961 442,239

Operating expenses:
Research and development 77,340 69,281
Sales and marketing 175,857 167,746
General and administrative, integration and other 76,210 88,672
Purchased in-process research and development - 830
Acquisition related intangible amortization 12,289 10,484
Total operating expenses 341,696 337,013

Income from operations 137,265 105,226

Other income (expense):
Interest income 2,541 7,391
Interest expense (22,136) (28,832)
Other income, net 5,249 (672)
Total other expense (14,346) (22,113)

Income before provision for income taxes and noncontrolling interest 122,919 83,113
Provision for income taxes 29,616 18,272
Net income 93,303 64,841
Less: Noncontrolling interest - 491
Net income attributable to QIAGEN N.V. $ 93,303 $ 64,350

Weighted average number of diluted common shares 205,096 204,999

Diluted net income attributable to QIAGEN N.V. per common share $ 0.45 $ 0.31

Diluted net income attributable to QIAGEN N.V. per common
share, adjusted $ 0.69 $ 0.58




QIAGEN N.V.
CONDENSED CONSOLIDATED BALANCE SHEETS

(in thousands, except par value) September 30,
2009
(unaudited) December 31,
2008

Assets

Current Assets:
Cash and cash equivalents $ 861,273 $ 333,313
Accounts receivable, net 181,692 158,440
Income taxes receivable 27,843 14,441
Inventories, net 133,618 108,563
Prepaid expenses and other 135,192 61,424
Deferred income taxes 32,543 27,374
Total current assets 1,372,161 703,555

Long-Term Assets:
Property, plant and equipment, net 310,215 289,672
Goodwill 1,273,754 1,152,105
Intangible assets, net 693,777 640,309
Deferred income taxes 78,016 73,766
Other assets 26,728 25,916
Total long-term assets 2,382,490 2,181,768

Total assets $ 3,754,651 $ 2,885,323

Liabilities and Shareholders' Equity

Current Liabilities:
Accounts payable $ 42,078 $ 48,836
Accrued and other liabilities 236,980 163,513
Income taxes payable 33,414 14,288
Current portion of long-term debt 50,000 25,000
Current portion of capital lease obligations 3,342 2,984
Deferred income taxes 10,256 7,754
Total current liabilities 376,070 262,375

Long-Term Liabilities:
Long-term debt, net of current portion 870,000 920,000
Capital lease obligations, net of current portion 28,797 29,718
Deferred income taxes 237,530 212,589
Other 13,945 6,797
Total long-term liabilities 1,150,272 1,169,104

Shareholders' Equity:
Common shares, EUR .01 par value:
Authorized--410,000 shares
Issued and outstanding--231,130 shares
in 2009 and 197,839 shares in 2008 2,697 2,212
Additional paid-in-capital 1,606,218 958,665
Retained earnings 571,115 477,812
Accumulated other comprehensive income 48,279 15,155
Total QIAGEN N.V. shareholders' equity 2,228,309 1,453,844

Total liabilities and shareholders' equity $ 3,754,651 $ 2,885,323



Three months ended September 30, 2009
(in thousands, except EPS data)

Operating
Income Pre-tax
Income
Net Sales Gross Profit Income Tax Net Income Diluted EPS*

Reported results $ 259,659 $ 173,012 $ 53,354 $ 49,319 $ (11,629) $ 37,690 $ 0.18

Adjustments:
Business integration, acquisition related
and restructuring costs - 177 2,790 2,790 (918) 1,872 0.01

Purchased intangibles amortization - 13,111 17,499 17,499 (6,082) 11,417 0.06

Share-based compensation - 245 2,348 2,348 (678) 1,670 0.01

Acquisition of DxS Ltd. - 2,515 5,784 5,784 (1,661) 4,123 0.02
Transfer of Olerup SSP business and other
acquisition related income - - - (2,429) (835) (3,264) (0.02)

Total adjustments - 16,048 28,421 25,992 (10,174) 15,818 0.08

Adjusted results $ 259,659 $ 189,060 $ 81,775 $ 75,311 $ (21,803) $ 53,508 $ 0.26

Using 208,316 diluted shares



Three months ended September 30, 2008
(in thousands, except EPS data)

Net Sales Gross Profit Operating
Income Pre-tax
Income Income Tax Net Income Diluted EPS*


Reported results $ 230,800 $ 152,939 $ 38,178 $ 27,846 $ (6,679) $ 20,791 $ 0.10

Adjustments:
Business integration, acquisition related
and restructuring costs - 396 9,122 9,122 (3,138) 5,984 0.03

Purchased in-process R&D - - 830 830 - 830 -

Purchased intangibles amortization - 12,776 16,794 16,794 (5,876) 10,918 0.06

Share-based compensation - 223 1,896 1,896 (580) 1,316 0.01

Acquisition related impairment - - - 4,000 (1,480) 2,520 0.01

Total adjustments - 13,395 28,642 32,642 (11,074) 21,568 0.11

Adjusted results $ 230,800 $ 166,334 $ 66,820 $ 60,488 $ (17,753) $ 42,359 $ 0.21



* Using 204,600 diluted shares



QIAGEN N.V.
RECONCILIATION OF REPORTED TO ADJUSTED FIGURES
(unaudited)

Nine months ended September 30, 2009
(in thousands, except EPS data)

Net Sales Gross Profit Operating
Income Pre-tax
Income Income Tax Net Income Diluted EPS*


Reported results $ 720,748 $ 478,961 $ 137,265 $ 122,919 $ (29,616) $ 93,303 $ 0.45

Adjustments:
Business integration, acquisition related
and restructuring costs - 688 10,705 10,705 (3,396) 7,309 0.04

Purchased intangibles amortization - 39,290 51,579 51,579 (17,973) 33,606 0.17
Share-based compensation - 699 7,352 7,352 (2,229) 5,123 0.02
Acquisition of DxS Ltd. - 2,515 5,784 5,784 (1,661) 4,123 0.02
Transfer of Olerup SSP business and other
-
acquisition related income - - (2,429) (835) (3,264) (0.02)
Acquisition related write-off of prepaid
expenses and other asset impairment - - - 2,703 (870) 1,833 0.01

Total adjustments - 43,192 75,420 75,694 (26,964) 48,730 0.24

Adjusted results $ 720,748 $ 522,153 $ 212,685 $ 198,613 $ (56,580) $ 142,033 $ 0.69



* Using 205,096 diluted shares


Nine months ended September 30, 2008
(in thousands, except EPS data)
Operating
Income Pre-tax
Income
Net Sales Gross Profit Income Tax Net Income Diluted EPS*

Reported results $ 655,794 $ 442,239 $ 105,226 $ 83,113 $ (18,272) $ 64,350 $ 0.31

Adjustments:
Business integration, acquisition related
and restructuring costs - 396 27,723 27,723 (9,760) 17,963 0.09

Purchased in-process R&D - - 830 830 - 830 -

Purchased intangibles amortization - 35,551 46,035 46,035 (16,306) 29,729 0.15

Share-based compensation - 763 6,251 6,251 (2,001) 4,250 0.02

Acquisition related impairment - - - 4,000 (1,480) 2,520 0.01

Total adjustments - 36,710 80,839 84,839 (29,547) 55,292 0.27

Adjusted results $ 655,794 $ 478,949 $ 186,065 $ 167,952 $ (47,819) $ 119,642 $ 0.58

* Using 204,999 diluted shares